Title:Systems Immunology Based Immune Engineering

Speaker:Dr. Ning Jenny Jiang

Inviter:Dr. Hui Yang

Time:2017.12.26 10:30 am-11:30 am

Address:The 1st Conference Room of the InternationalConference Center, Youyi Campus of Northwestern Polytechnical University

Abstract

Adaptive immune system is critically important for infection, vaccination, aging, auto-immune diseases, and cancer and cancer immunotherapy. Although detailed molecular mechanisms have been studied intensively in many areas of the adaptive immune system, the immune repertoire – the cellular makeup of the adaptive immune system – has not yet been comprehensively characterized due to many technical limitations. In this talk, Dr. Jiang will first introduce several technologies that they developed to profile the adaptive immune system. Then, she will give examples on how this in depth understanding will facilitate the immune engineering and therapeutics development.

Biography

Dr. Jiang is an assistant professor in the Department of Biomedical Engineering at the University of Texas at Austin. She obtained her Ph.D. from Georgia Institute of Technology where she studied molecular mechanisms of how T cell receptors recognize pMHC Ligands. Before joining the faculty at UT Austin in January 2012, she was a postdoctoral fellow in Dr. Stephen Quake’s lab at Stanford University where she developed a technology using high-throughput sequencing to quantitatively profile the antibody repertoire. Her lab at UT Austin focuses on systems immunology by combining these technologies to profile immune repertoire in cancer and vaccination to establish a set of metrics for immune health. Dr. Jiang is the recipient of the prestigious NIH Pathway to Independence Award (K99/R00), Cancer Prevention and Research Institute of Texas, Damon Runyon-Rachleff Innovator, and NSF CAREER Award.